Table 2. Changes in HF Parameters from Admission to Discharge According to Patient Cluster*.
Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | Baseline | Follow-up | Change | p-value | Baseline | Follow-up | Change | p-value | Baseline | Follow-up | Changes | p-value | Baseline | Follow-up | Change | p-value |
RAP† mmHg | 13 (8, 18) | 8 (5, 12) | -5 (-9, 0) | <0.001 | 11 (6, 14) | 7 (3,11) | -3 (-7,-1) | <0.001 | 17 (13,22) | 8 (5,10) | -10 (-14,-5) | <0.001 | 14 (9,20) | 8 (5,11) | -4 (-7,0) | 0.007 |
PCWP‡ mmHg | 27 (19, 34) | 17 (12, 21) | -11 (-18, -3) | <0.001 | 22 (15,28) | 15 (10,18) | -8 (-14,2) | <0.001 | 32 (28,38) | 15 (12,19) | -16 (-23,-9) | <0.001 | 23 (20–27) | 17 (16,20) | -5 (-10,0) | 0.001 |
CI, L/min/m2 | 1.9 (1.6, 2.3) | 2.2 (1.9, 2.5) | 0.4 (-0.1, 0.8) | <0.001 | 2 (1.5,2.2) | 2.4 (1.9,2.7) | 0.4 (0.1,0.7) | 0.005 | 1.6 (1.2,2.2) | 2.2 (1.9,2.4) | 0.6 (0.3,1.0) | <0.001 | 1.8 (1.6–2.5) | 2.4 (1.9,2.8) | 0.3 (0,0.9) | 0.054 |
BNP, pg/mol | 469 (174, 963) | 344 (138, 681) | -79 (-362,2) | 0.095 | 489 (183, 860) | 232 (135, 610) | -71 (-269,15) | 0.04 | 877 (89, 1391) | 319 (147, 662) | -335 (-741,30) | 0.004 | 1398 (518, 4513) | 632 (308,1727) | -365 (-1373,-9) | 0.003 |
Cr, mg/dL | 1.4 (1.2, 1.6) | 1.4 (1.2–1.7) | 0 (-0.2,0.2) | 0.365 | 0.9 (0.9,1.2) | 1.1 (0.8,1.5) | 0 (-0.1,0.2) | 0.045 | 1.4 (1.3,1.8) | 1.3 (1.1,1.7) | -0.1 (-0.3,0.3) | 0.66 | 2.5 (2.1–3.1) | 2 (1.8,2.5) | -0.4 (-0.8,0.2) | 0.023 |
Cr indicates creatinine; All other abbreviations can be found in Table 1.
*Values are median interquartile range.
†Change between baseline and optimal measurement just prior to PAC removal.
‡Change between baseline and 1 month.