Fig 7. Histopathological changes in dogs resulting from infections.

Rows 1–5 represent tissue samples collected from controls, E. canis, E. chaffeensis, A. platys and A. phagocytophilum infected dogs, respectively. A) Lung tissues showing perivascular infiltration of macrophages and lymphocytes with variation in the degree of inflammation among infected groups compared to controls. B) Liver tissues having periportal infiltrates of lymphocytes and macrophages with variation in the degree of inflammation observed among infected groups compared to controls. C) Spleen tissues showing periarteriolar lymphoid sheet (white pulp) hyperplasia with variation in the size of the white pulp in infected groups compared to controls. One section each of randomly selected samples with magnifications of 200x for lung, 400x of liver and 20x of spleen were presented.