Table 1.

Criteria and Prevalence for Consensus Definitions of Sarcopenia in the Osteoporotic Fractures in Men (MrOS) Study

	Slowness Definition	Prevalence	Weakness Definition	Prevalence	Low lean mass Definition	Prevalence	Summary definition Definition	Prevalence
International Working Group (IWG)	Gait speed <1.0 m/s	17.4% (N=1034)	Not included	N/A	ALM/ht2 ≤7.23 kg/m2	20.9% (N=1239)	Sarcopenia: both slowness and low lean mass	4.7% (N=277)
European Working Group on Sarcopenia Older Persons (EWGSOP)	Gait speed ≤0.8 m/s	4.4% (N=262)	Grip strength <30 kg	8.0% (N=474)	ALM/ht2 ≤7.23 kg/m2	20.9% (N=1239)	1) Sarcopenia: low lean mass plus either slowness or weakness 2) Severe sarcopenia: all three criteriaa	1) 4.3% (N=257) 2) 0.4% (N=26)
Foundation for the NIH (FNIH) Sarcopenia Project primary definition	Gait speed ≤0.8 m/s	4.4% (N=262)	Grip strength <26 kg	3.9% (N=233)	ALM/BMI <0.789b	17.3% (N=1025)	1) weakness and low lean mass 2) slowness with weakness and low lean mass	1) 1.5% (N=88) 2) 0.3% (N=18)
Baumgartner	Not included	N/A	Not included	N/A	ALM/ht2 ≤7.23 kg/m2	20.9% (N=1239)	Presence of low lean mass	20.9% (N=1239)
Newman	Not included	N/A	Not included	N/A	Residual of actual ALM - predicted ALM from equationc	20.0% (N=1186)	Presence of low lean mass	20.0% (N=1186)

^aSince prevalence of EWGSOP severe sarcopenia was low, both sarcopenia and severe sarcopenia were analyzed together

^bThe FNIH Sarcopenia Project also proposed an alternative definition using ALM<19.75 kg for low lean mass (prevalence: 8.9%, N=525). Using the alternative definition, prevalence of “weakness and low lean mass” was 1.1% (N=67) and prevalence of “slowness with weakness and low lean mass” was 0.3% (N=16).

^cThe equation used to calculate residuals was ALM (kg) =− 22.48 +24.14*height(m) + 0.21*total fat mass (kg) as derived for men in the Health ABC study (17); the cut-point for the residual was ≤−0.204 kg/m²

ALM=appendicular lean mass, NIH = National Institute of Health