Fig. 3.

Set of four serum biomarkers, COPS2, CTSF, NT5E, and TERF1, were specific for gastric cancer but not for other gastric diseases. A, characteristics of study participants of GU/GP/chronic atrophic gastritis group. B–E, comparison of the GU/GP/CAG group, healthy people, and GC patient. All 314 cases were classified into the GU, GP, CAG, or other diseases group on the basis of clinical information. The signals of each of the four candidates are as follows: B, COPS2; C, CTSF; D, NT5E; and E, TERF1 reacting with the sera in each case are shown. (The y axis is log10 scale.) Asterisks indicate statistical difference as compared to the GC group (p < 0.05).