Skip to main content
. 2016 Feb 3;11(2):e0147845. doi: 10.1371/journal.pone.0147845

Table 1. Micro CT analysis of femur bone structure changes in control, Fgfr1PT-cKO, and Fgfr1DT-cKO mice.

Femur Control Fgfr1PT-cKO Control Fgfr1DT-cKO
Trabecular Bone Volume (mm3) 0.328 ± 0.019 0.1863 ± 0.093* 0.273 ± 0.145 0.235 ± 0.056
Trabecular Bone Fraction (BV/TV) 0.177 ± 0.017 0.101 ± 0.052* 0.156 ± 0.075 0.131 ± 0.033
Trabecular Number (1/mm) 3.813 ± 0.156 3.428 ± 0.543 4.302 ± 0.797 4.394 ± 0.567
Trabecular Thickness (mm) 0.049 ± 0.004 0.043 ± 0.01 0.050 ± 0.006 0.043 ± 0.002*
Trabecular Material BMD (mgHA/mm3) 913.1 ± 21.3 896.1 ± 28.2 896.6 ± 19.2 859.7 ± 8.9**
Cortical Thickness (mm) 0.204 ± 0.011 0.203 ± 0.006 0.196 ± 0.012 0.179 ± 0.013*

Data were presented as mean ± S.D. from mice (n = 5) of each genotype. One-tail unpaired t test

*P<0.05,

**P<0.01 vs control.