Table 3. Association of OW, HT, DL and IGT in cervical, thoracic and lumbar region, respectively.
| Cervical | Thoracic | Lumbar | |||||
|---|---|---|---|---|---|---|---|
| OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | ||
| Overweight | Yes vs no | 1.28 (0.92–1.78) | 0.1397 | 1.75 (1.24–2.51) * | 0.0016 | 1.87 (1.06–3.48) * | 0.0306 |
| Hypertension | Yes vs no | 1.19 (0.85–1.66) | 0.286 | 1.54 (1.09–2.18) * | 0.0138 | 0.88 (0.52–1.45) | 0.6189 |
| Dyslipidemia | Yes vs no | 1.06 (0.49–2.17) | 0.8853 | 0.42 (0.21–0.86) * | 0.0176 | 0.87 (0.34–2.70) | 0.7963 |
| Impaired Glucose Tolerance | Yes vs no | 1.27 (0.88–1.85) | 0.1943 | 1.65 (1.12–2.48) * | 0.0115 | 1.48 (0.80–2.95) | 0.2211 |
| Age | over 65 vs under 65 | 2.98 (2.16–4.11) * * * | <0.0001 | 5.76 (4.10–8.16) * * * | <0.0001 | 4.72 (2.47–9.69) * * * | <0.0001 |
| Sex | Women vs men | 1.32 (0.92–1.90) | 0.1342 | 1.02 (0.70–1.48) | 0.9198 | 0.95 (0.56–1.66) | 0.8691 |
| Regional difference | Mountainous town vs seacoast town | 1.75 (1.13–2.78) * | 0.012 | 1.20 (0.77–1.89) | 0.4353 | 0.14 (0.07–0.27) * * * | <0.0001 |
| Smoking habit | Yes vs no | 0.88 (0.54–1.44) | 0.6002 | 0.90 (0.54–1.49) | 0.6707 | 0.56 (0.29–1.12) | 0.0984 |
| Alcohol consumption | Yes vs no | 0.94 (0.67–1.33) | 0.7332 | 0.96 (0.67–1.37) | 0.8332 | 0.92 (0.55–1.55) | 0.7456 |
Multivariable logistic regression analysis was performed to determine the association of OW, HT, DL, and IGT with DD. The DD in the cervical, thoracic, or lumbar region was separately served as an objective variable. DD = disc degeneration, OW = Overweight, HT = Hypertension, DL = Dyslipidemia, IGT = Impaired Glucose Tolerance. Overweight was diagnosed as BMI ≥ 25, Hypertension was diagnosed as systolic BP ≥ 130 mm Hg and/or diastolic BP ≥ 85 mm Hg, DL was diagnosed as serum HDL-C level < 40 mg/dl, Impaired Glucose Intolerance was diagnosed as serum HbA1c level ≥ 5.5%
OR = odds ratio, 95% CI = 95% confidence interval
*p value < 0.001
***p value < 0.0001