Table 2. Results from the multivariable logistic regression examining the factors associated with receipt of surgical therapy among patients with hepatocellular carcinoma.
Predict variables | Adjusted OR | 95% CI | P |
---|---|---|---|
Race | |||
White | 1 | – | Reference |
Black | 1.06 | 0.76-1.48 | 0.73 |
Native American | 1.33 | 0.55-3.16 | 0.53 |
Asian | 1.48 | 1.13-1.95 | 0.01 |
Age (year) | |||
18-39 | 7.6 | 1.02-56.69 | 0.05 |
40-59 | 1 | – | Reference |
60-69 | 0.71 | 0.56-0.89 | 0.004 |
≥70 | 0.42 | 0.31-0.56 | <0.001 |
Gender | |||
Male | 1 | – | Reference |
Female | 1.43 | 1.10-1.87 | 0.01 |
Tumor size (cm) | 1 | 1.00-1.01 | 0.01 |
Tumor grade | |||
I/II | 1 | – | Reference |
III/IV | 1.71 | 1.26-2.33 | 0.001 |
Stage at diagnosis | |||
Localized | 1 | – | Reference |
Regional spread | 0.74 | 0.58-0.96 | 0.02 |
Distant spread | 0.21 | 0.11-0.39 | <0.001 |
Unstaged | NA | NA | NA |
AFP | |||
Negative | 1 | – | Reference |
Positive | 0.64 | 0.51-0.80 | <0.001 |
Cirrhosis | |||
F0 | 1 | – | Reference |
F1 | 0.6 | 0.47-0.77 | <0.001 |
OR, odds ratio; CI, confidence interval; tumor grade I, well differentiated; tumor II, moderately differentiated; tumor III, poorly differentiated; tumor IV, undifferentiated; NA, not applicable; AFP, alpha fetal protein; F0, fibrosis score 0-4, none to moderate fibrosis; F1, fibrosis score 5-6, severe fibrosis or cirrhosis.