Figure 1.

Recruitment flow chart. There were 129 bronchiectasis patients at baseline measurements and during longitudinal follow-up. A total of 101 bronchiectasis patients were followed-up for 1 year, and 65 patients (56 patients with non-significant bronchodilator responses, 9 patients with significant bronchodilator responses) were included in the analysis of the lung function trajectories and bronchiectasis exacerbations. BEs were defined as having 3 of the following items that persisted for at least 24 h: significantly increased sputum purulence/volume; dyspnea; considerably increased cough frequency; T >37.5 °C; hemoptysis; exercise intolerance or fatigue; increased crackles; increased pulmonary infiltrations. BDR, bronchodilator response.