Table 3. Univariate analyses for post-recurrence survival in 141 patients.
| Variables | HR | 95% CI | P value |
|---|---|---|---|
| Sex | 0.394 | ||
| Male | 1 | ||
| Female | 0.808 | 0.494–1.319 | |
| Age at recurrence | 1.008 | 0.984–1.033 | 0.535 |
| Comorbidity number | 0.476 | ||
| 0 or 1 | 1 | ||
| ≥2 | 1.192 | 0.735–1.932 | |
| Tumor size | 1.078 | 0.956–1.215 | 0.223 |
| Resection type | 0.002 | ||
| Lobectomy | 1 | ||
| Bilobectomy/pneumonectomy | 1.984 | 1.294–3.041 | |
| Cell type | 0.632 | ||
| Adenocarcinoma | 1 | ||
| Squamous cell carcinoma | 0.735 | 0.391–1.381 | |
| Others | 0.774 | 0.404–1.485 | |
| Histologic grade | 0.010 | ||
| Poor | 1.852 | 1.157–2.965 | |
| Moderate/well | 1 | ||
| Stage | 0.174 | ||
| IA | 1 | ||
| IB | 1.954 | 1.050–3.638 | |
| IIA | 1.662 | 0.768–3.597 | |
| IIB | 1.878 | 1.015–3.473 | |
| N stage | 0.507 | ||
| N0 | 1 | ||
| N1 | 1.145 | 0.767–1.708 | |
| Disease free interval | 0.073 | ||
| ≤1 year | 1.429 | 0.967–2.112 | |
| >1 year | 1 | ||
| Symptom at the initial recurrence | 0.000 | ||
| No | 1 | ||
| Yes | 2.951 | 1.944–4.478 | |
| Recurrence pattern | 0.109 | ||
| Local | 1 | ||
| Distant | 1.638 | 1.034–2.594 | |
| Both | 1.438 | 0.691–2.991 | |
| Pulmonary metastasis | 0.007 | ||
| No | 1.766 | 1.169–2.668 | |
| Yes | 1 | ||
| Mediastinal LN metastasis | 0.319 | ||
| No | 1 | ||
| Yes | 1.235 | 0.815–1.870 | |
| Post-recurrence therapy | 0.001 | ||
| No | 2.304 | 1.427–3.719 | |
| Yes | 1 |
HR, hazard ratio; CI, confidence interval.