Table 6. Association of chromosome 2q34 Locus (rs715) with Risk of CAD in the CARDIoGRAM Consortium.
| Group | n | Effect allele frequency | OR (95% CI) | P–value |
|---|---|---|---|---|
| Females | 26,905 | 0.30 | 0.88 (0.83–0.94) | 6.3 × 10−5 |
| Males | 26,772 | 0.31 | 1.00 (0.96–1.05) | 0.95 |
| Combined | 53,667 | 0.31 | 0.95 (0.92–0.99) | 0.01 |
CAD, coronary artery disease; CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.
Association results are shown for the C allele of rs715. Analyses with all subjects were adjusted for age and sex, whereas sex-stratified analyses were only adjusted for age.