Table 1.

Characteristics of newly diagnosed (2002-2004) SLE patients^a in the Georgia Lupus Registry, overall and by all-cause end-stage renal disease status through 4/30/11

		Overall (n=344)	ESRD status as of 4/30/11b
Characteristic	N		Yes (n=29)	No (n=315)	P c
Age at diagnosis of SLE, mean (SD)	344	36.4 (16.4)	31.4 (17.7)	36.9 (16.2)	0.08
Sex, %	344				>0.9
Male		45 (13.1%)	3 (10.3%)	42 (13.3%)
Female		299 (86.9%)	26 (89.7%)	273 (86.7%)
Race,d %	330				0.04
White		79 (23.9%)	2 (7.1%)	77 (25.5%)
Black		251 (76.1%)	26 (92.9%)	225 (74.5%)
% HS dropouts in census tract, median (IQR)	299	13.2 (6.6- 22.8)	14.9 (9.5- 31.2)	11.7 (6.6- 21.9)	0.06
% poor in census tract, median (IQR)	299	11.1 (5.8- 22.6)	13.8 (6.7- 25.8	10.7 (5.5- 20.5)	0.29
Early lupus nephritis, %	344				<0.001
No		225 (65.4%)	6 (20.7%)	219 (69.5%)
Yes		119 (34.6%)	23 (79.3%)	96 (30.5%)
No. of ACR criteria, %	344
≤3		78 (22.7%)	74 (23.5%)	4 (13.8%)	0.03
4		121 (35.2%)	115 (36.5%)	6 (20.7%)
≥5		145 (42.2%)	126 (40.0%)	19 (65.5%)

ESRD, end-stage renal disease; SLE, systemic lupus erythematosus; IQR, inter-quartile range; HS, high school. Early lupus nephritis was defined by urine or biopsy evidence or treatment rheumatologist or nephrologist documentation of lupus nephritis in the medical record, by 2005. Poor was defined as living below 100% federal poverty threshold.

^aBy combined case definition: ≥4 ACR criteria, 3 ACR criteria plus treating rheumatologist’s diagnosis, or renal involvement as indicated by biopsy consistent with class II-VI lupus nephritis or ESRD requiring dialysis or renal transplantation.

^bLast date of death follow-up in the Georgia Lupus Registry. A total of 30 patients initiated ESRD treatment between date of SLE diagnosis and 9/30/12, the last date of ESRD follow-up.

^cBy Fisher’s exact test or Wilcoxon rank test across ESRD status.

^dRestricted to white and black patients only, due to small numbers of patients of other races (Asian, n=11, 1 event; missing race, n=2, 0 events).