Table 1.

Cross Disease and Disease Specific Measures

Data and Outcomes	# items	Time required (minutes)	Baseline	7 Days	6 month	Mode of Administration
Generic Measures
Socio-demographic Form	9	<5	X	--	--	Self-report
Clinical Information Form	19	<5	X	--	X	Interviewer
Karnofsky Performance Status	1	<2	X	--	X	Medical Prof Rated
Oral Digit Symbol Modalities	0-133	<3	X	--	X	Interviewer
Global HRQL Question	1	<2	X	--	X	Self-report
Global Rating of Change Scores	1	<2	--	--	X	Self-report
EQ-5D	15	<3	x	--	x	Self-report
PROMIS Global Health Scale	10	<2	x	--	x	Self-report
Neuro-QOL Short Forms and Scales
Neuro-QOL Short Forms and Scales	±100	45-60	X	X	X	Self-Report
Multiple Sclerosis Specific Mesures
Multiple Sclerosis Functional Composite (MSFC) (substitute OSDM for PASAT)	4	<5	X	--	X	Self-report / Interviewer
Functional Assessment in Multiple Sclerosis (FAMS)	44	10	X	--	X	Self-report
Multiple Sclerosis Performance Scale (MSPS)	8	<5	X	--	X	Self-report