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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Mult Scler. 2015 Aug 3;22(6):830–841. doi: 10.1177/1352458515599450

TABLE 6.

Responsiveness to Global Ratings of Change Questions

Physical Social/Family Emotional Cognitive Symptomatic Overall QOL
Freq. Percent Freq. Percent Freq. Percent Freq. Percent Freq. Percent Freq. Percent
Better 25 15.5 32 19.9 34 21.1 17 10.6 25 15.5 36 22.4
About the same 67 41.6 89 55.3 71 44.1 88 54.7 64 39.8 73 45.3
Worse 39 24.2 10 6.2 26 16.2 26 16.2 42 26.1 22 13.7
Missing 30 18.6 30 18.6 30 18.6 30 18.6 30 18.6 30 18.6
F p F p F p F p F p F p
Neuro-QOL PHYSCIAL CONSTRUCTS
Lower Extremity (Mobility)* 0.947 0.391 0.004 0.996 0.021 0.980 2.050 0.134 1.937 0.149 0.367 0.694
Upper Extremity (Fine Motor, ADL)* 1.697 0.187 1.241 0.293 1.096 0.337 4.762 0.010 0.936 0.395 2.510 0.085
Fatigue 2.362 0.098 3.423 0.036 3.659 0.029 9.750 0.000 6.452 0.002 3.121 0.048
Sleep Disturbance 0.865 0.423 1.263 0.286 1.352 0.263 2.593 0.079 2.134 0.123 1.046 0.354
Neuro-QOL EMOTIONAL CONSTRUCTS
Depression 5.604 0.005 4.173 0.018 14.818 0.000 2.492 0.087 5.019 0.008 8.991 0.000
Anxiety 5.365 0.006 2.195 0.116 7.282 0.001 1.909 0.152 2.164 0.119 5.573 0.005
Stigma 1.795 0.170 3.978 0.021 3.358 0.038 3.732 0.027 2.533 0.083 4.048 0.020
Positive Affect and Well-Being* 5.897 0.004 9.480 0.000 17.068 0.000 11.110 0.000 10.185 0.000 13.101 0.000
Emotional and Behavioral Dyscontrol 2.832 0.063 3.449 0.035 3.187 0.045 1.480 0.231 3.140 0.047 3.395 0.037
Neuro-QOL COGNITIVE CONSTRUCTS
Applied Cognition- General Concerns* 2.123 0.124 0.263 0.769 0.848 0.431 7.086 0.001 0.056 0.945 1.050 0.353
Applied Cognition- Executive Function* 3.298 0.040 0.239 0.788 0.683 0.507 4.694 0.011 0.607 0.547 1.235 0.294
Neuro-QOL SOCIAL CONSTRUCTS
Ability to Participate in Social Roles and Activities* 2.159 0.120 0.438 0.646 2.355 0.099 2.391 0.096 1.276 0.283 3.915 0.022
Satisfaction with Social Roles and Activities* 1.775 0.174 0.559 0.573 0.563 0.571 1.906 0.153 0.536 0.586 1.768 0.175

‡ df1=2:# , df2 between 95 and 128

*

For these banks, a high score indicates better function, for all other banks a high score indicates wore function SEE Line on next p≤0.05 considered moderately significant (bolded); p≤0.001 considered strongly significant (bolded and italicized)