Fig. 5.

Fecal transfer via gavage results in suppression of non-aerobic resting metabolic rates. A) C57BL/6 female donor mice were maintained on standard chow with ad libitum access to water (n = 4) or water with risperidone (20 mg/ml, n = 5) for nine weeks. Fecal material from donor mice was transferred by gavage to naive recipients (n = 7 for risperidone and n = 6 for control) daily for 14 days. Risperidone measured by HPLC in donor stool indicated that recipient mice received only 8.7 ± 1 ng/ml risperidone/day. Following fecal transfer, total and aerobic RMR was measured in recipient mice. B) Total RMR in fecal transfer recipients. C) Combined calorimetry determined the aerobic and non-aerobic components of total resting metabolic rate. Data are representative of mean ± s.e.m. *p < 0.05.