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. 2016 Feb 4;10:4. doi: 10.3389/fnins.2016.00004

Figure 3.

Figure 3

CIH alters neuronal excitability coupled to the network rhythm. (A) Representative traces paired recordings of the integrated preBötC network rhythm (∫,top) and membrane potential (Vm) of an individual preBötC neuron participating with the network (bottom) from a control slice. (B) Representative traces of paired recordings from two individuals slices illustrating the change in firing pattern during network activity and fidelity of individual preBötC neurons relative to the network rhythm following CIH. The yellow box highlights the lack of action potential generation from the preBötC neuron during network burst (top pair). The pink box highlights robust action potential generation from a preBötC neuron occurring during a smaller subnetwork network burst (bottom pair). Vertical Scale Bars: 10 mV; Horizontal Scale Bars: 500 ms. (C) Summarized data shows that, in aggregate, number of action potentials generated by individual preBötC neurons during the network burst is reduced following CIH.