Table 3.
Level of inflammatory mediators in acute and chronic group
| Meniscus (pg/mg) | Synovium (pg/mg) | ||||||
|---|---|---|---|---|---|---|---|
| IM | NIM | p - value | NS | FS | p - value | ||
| Mean | Mean | ||||||
| TNF-α | Acute | 0.44 ± .14 | 0.044 ± .007 | .043 | 0.055 ± .004 | 0.053 ± 0.053 | n.s. |
| Chronic | 0.059 ± .042 | 0.049 ± .022 | .03 | 0.055 ± .006 | 0.055 ± .006 | n.s. | |
| IL-6 | Acute | 0.12 ± .03 | 0.055 ± .014 | .043 | 0.087 ± .02 | 0.051 ± .14 | .043 |
| Chronic | 0.096 ± .017 | 0.071 ± .012 | .03 | 0.088 ± .007 | 0.082 ± .014 | .015 | |
| NGF | Acute | 0.049 ± .082 | 0.042 ± .084 | n.s. | 0.053 ± .01 | 0.061 ± .017 | n.s. |
| Chronic | 0.042 ± .004 | 0.042 ± .005 | n.s. | 0.057 ± .02 | 0.061 ± .03 | n.s. | |
TNF-α tumor necrosis factor-alpha, IL-6 interleukin-6, NGF nerve growth factor, IM injured meniscal site, NIM non-injured meniscal site, NS synovium ‘nearest’ the lesion, FS ‘farthest’ synovium, n.s. not significantly different, SD standard deviation