Table 4.
Level of inflammatory mediators in male and female
| Meniscus (pg/mg) | Synovium (pg/mg) | ||||||
|---|---|---|---|---|---|---|---|
| IM | NIM | p - value | NS | FS | p - value | ||
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | ||||
| TNF-α | Male | 0.12 ± .053 | 0.048 ± .03 | .018 | 0.055 ± .002 | 0.055 ± .002 | n.s. |
| Female | 0.23 ± .11 | 0.046 ± .004 | .04 | 0.054 ± .002 | 0.053 ± .002 | n.s. | |
| IL-6 | Male | 0.079 ± .069 | 0.068 ± .014 | .049 | 0.088 ± .0021 | 0.075 ± .0072 | .003 |
| Female | 0.14 ± .034 | 0.065 ± .012 | .018 | 0.089 ± .0034 | 0.072 ± .011 | .018 | |
| NGF | Male | 0.041 ± .005 | 0.041 ± .006 | n.s. | 0.061 ± .001 | 0.054 ± .003 | n.s. |
| Female | 0.044 ± .0072 | 0.048 ± .0067 | n.s. | 0.062 ± .012 | 0.06 ± .02 | n.s. | |
TNF-α tumor necrosis factor-alpha, IL-6 interleukin-6, NGF nerve growth factor, IM injured meniscal site, NIM non-injured meniscal site, NS synovium ‘nearest’ the lesion, FS ‘farthest’ synovium, n.s. not significantly different, SD standard deviation