. 2016 Feb 3;23:4. doi: 10.1051/parasite/2016004

Table 1.

Cellular proliferation and cytokine production by splenocytes isolated from ROP17 DNA-immunized BALB/c mice and controls.

Groups^*	Cytokine production (pg/mL)^**				Lymphocyte SI
Groups^*	IFN-γ	IL-2	IL-4	IL-10
PBS	41.29 ± 6.73^a	79.26 ± 5.35^a	78.84 ± 4.37^a	63.31 ± 5.13^a	1.02 ± 0.11^a
p3×Flag-CMV-14	45.17 ± 6.93^a	81.14 ± 5.71^a	76.63 ± 5.15^a	66.457 ± 5.26^a	1.163 ± 0.12^a
p3×Flag-CMV-14-ROP17	186.17 ± 11.47^b	158.41 ± 11.38^b	75.63 ± 2.73^a	70.25 ± 4.74^a	2.14 ± 0.23^b

n = 6 per group.

^**

Splenocytes were harvested from the mice 2 weeks after the final immunization. Results are presented as means ± the standard errors of three replicate experiments. Values for IFN-γ are for 96 h, values for IL-10 are for 72 h, and values for IL-2, IL-4 are for 24 h. Letter a indicates no statistical difference was observed (P > 0.05), and letter b means significant difference within each cytokine or lymphocyte SI group (compared with PBS or empty vector group, P < 0.05).