Table 1. Comparison of the Antimicrobial Susceptibilities of TRNG and Non-TRNG Isolates during 2004–2007, 2008–2009, and 2010–2011.
Antimicrobial agent | TRNG isolates | Non-TRNG isolates | ||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2004-2007 (14) | 2008-2009 (27) | 2010-2011 (17) | Total (58) | 2004-2007 (115) | 2008-2009 (136) | 2010-2011 (53) | Total (304) | |||||||||||||||||
MIC50 | MIC90 | % S | MIC50 | MIC90 | % S | MIC50 | MIC90 | % S | MIC50 | MIC90 | % S | MIC50 | MIC90 | % S | MIC50 | MIC90 | % S | MIC50 | MIC90 | % S | MIC50 | MIC90 | % S | |
Penicillin* | 0.25 | 1 | 0 | 0.25 | >128 | 0 | 1 | >128 | 0 | 0.25 | >128 | 0 | 2 | 8 | 0 | 1 | 32 | 0 | 1 | 64 | 0 | 2 | 8 | 0 |
Ceftriaxone | ≤0.008 | ≤0.008 | 100 | ≤0.008 | 0.06 | 100 | 0.03 | 0.06 | 100 | ≤0.008 | ≤0.008 | 100 | 0.06 | 0.12 | 100 | 0.03 | 0.12 | 100 | 0.03 | 0.12 | 100 | 0.06 | 0.12 | 100 |
Cefixime | ≤0.008 | ≤0.008 | 100 | ≤0.008 | 0.06 | 100 | 0.06 | 0.25 | 100 | ≤0.008 | ≤0.008 | 100 | 0.06 | 0.12 | 99 | 0.03 | 0.12 | 100 | 0.03 | 0.12 | 98 | 0.06 | 0.12 | 100 |
Spectinomycin | 32 | 32 | 100 | 32 | 32 | 100 | 16 | 32 | 100 | 32 | 32 | 100 | 32 | 32 | 100 | 32 | 32 | 100 | 16 | 32 | 100 | 32 | 32 | 100 |
Ciprofloxacin | ≤0.008 | 0.12 | 93 | 2 | 8 | 44 | 4 | 16 | 18 | ≤0.008 | 4 | 61 | 8 | 16 | 10 | 8 | 16 | 16 | 4 | 32 | 6 | 8 | 16 | 15 |
TRNG, high-level tetracycline-resistant Neisseria gonorrhoeae; MIC, minimum inhibitory concentration (mg/L).
*The rates of penicillinase-producing strains of Neisseria gonorrhoeae were 11% in the non-TRNG isolates and 17% in the TRNG isolates.