Table 4. Changes in Pulmonary Function at Diagnosis of BOS.
Variable | Pretransplant | At diagnosis | p value |
---|---|---|---|
FVC, % predicted | 91.86±14.39 | 61.58±16.09 | <0.001 |
FEV1, % predicted | 91.81±14.71 | 40.25±21.61 | <0.001 |
FEV1/FVC, % | 83.81±9.81 | 53.17±22.63 | <0.001 |
TLC, % predicted | 97.81±12.12 | 93.45±16.16 | 0.060 |
RV, % predicted | 119.97±33.22 | 179.33±55.02 | <0.001 |
RV/TLC, % | 33.36±11.86 | 52.36±10.49 | <0.001 |
DLCO, % predicted | 77.00±16.78 | 53.35±20.59 | <0.001 |
BOS, bronchiolitis obliterans syndrome; DLCO, carbon monoxide diffusion in the lung; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; RV, residual volume; TLC, total lung capacity.