Figure 1.

Complex axonal arborisation of midbrain dopaminergic neurons. (A) Medial, dorsal, and frontal reconstructions of the axonal projections of midbrain dopaminergic neurons generated using a GFP protein targeting neuronal membranes. Red (striosome) and blue (matrix) lines indicate the striatal compartments in which axonal fibres are located. (B) Striatal arborisation of a typical midbrain dopaminergic neuron projected onto the parasagittal plane. Figures adapted from Matsuda et al.[13] with permission from the Society for Neuroscience. Abbreviations: ac, anterior commissure; cc, corpus callosum; cp, cerebral peduncle; CPu, caudate-putamen (neostriatum); GPe, external segment of the globus pallidus; GPi, globus pallidus interna; Hpc, hippocampus; ic, internal capsule; LV, lateral ventricle; ml, medial lemniscus; ot, optic tract; SNc, substantia nigra pars compacta; SNr, substantia nigra pars reticulata; STh, subthalamic nucleus; str, superior thalamic radiation; Th, thalamus; ZI, zona incerta.