Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 2;7:10190. doi: 10.1038/ncomms10190

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Transient outward current (Ito) was obtained by a family of depolarization steps from −80 mV, and was measured as the 4-aminopyridine (4-AP)-sensitive peak current (10 mM). (left upper) Voltage protocol. Right panel shows the representative recordings of 4-AP sensitive currents of the control (CTL) and KCNIP1 knockdown (KCNIP1 KD) atrial myocytes, respectively. (left lower) Efficiency of knockdown represented by decreased KCHIP1 protein level. (b) Representative current density–voltage relationships of 4-AP sensitive currents in CTL and KCNIP1 KD atrial myocytes. N=3 experiments for each group. Error bars, s.d. Full-length blots are presented in Supplementary Fig. 7.