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. 2016 Feb 4;6:20408. doi: 10.1038/srep20408

Figure 3. SUN1 but not KASH5 depletion triggers the DNA damage response.

Figure 3

(A) Localization of γH2AX and p-CHK1 in the nuclei of GV stage oocytes with either SUN1 or KASH5 knocked down or respective controls. Red: γH2AX; Blue: DNA; Green: p-CHK1. (B) Quantification of γH2AX levels in nuclei determined by relative fluorescence intensity in SUN1 or KASH5 knockdown groups and respective controls. (C) Quantification of p-CHK1 levels in nuclei determined by relative fluorescence in SUN1 or KASH5 knockdown groups and respective controls.