Table 3. Z-score for participation within key pathways.
| Root | Z-score |
|---|---|
| AKT1 | 2.777 |
| IL12B | 2.585 |
| EGFR | 2.521 |
| MAPK14 | 2.265 |
| TIAM1 | 2.073 |
| SGK1 | 1.498 |
| RFC1 | 1.434 |
| SEMA7A | 1.306 |
| NOS3 | 1.115 |
| VAV1 | 1.051 |
| PLA2G4A | 0.923 |
| CLPP | 0.859 |
| MMAA | 0.795 |
| CDK7 | 0.667 |
| LIPF | 0.411 |
| MAP2K2 | 0.220 |
| PREP | 0.156 |
| FAP | −0.164 |
| PDK2 | −0.867 |
| PRKAB1 | −1.442 |
| BPHL | −1.570 |
Calculated by normalizing participation score against the mean of the R-control set. Higher participation indicates that the intermediate nodes of the network are involved in key pathways to a greater extent.