Table 2. Classification of differentially abundant proteins (identified using ≥ 2 peptides) in the IFM compared to the FM of young tendon.
Higher in Young IFM | Higher in Young FM | ||
---|---|---|---|
ECM Proteins | Total Protein Number | 48 | 12 |
Collagens | 1 (2.1%) | 3 (25.0%) | |
Glycoproteins | 5 (10.4%) | 5 (41.7%) | |
Proteoglycans | 1 (2.1%) | 1 (8.3%) | |
ECM regulators | 0 | 1 (8.3%) | |
ECM-affiliated | 2 (4.2%) | 0 | |
Secreted factors | 0 | 0 | |
Total | 9 (18.8%) | 10 (83.3%) | |
Non-ECM proteins | Cytoskeletal | 19 (39.6%) | 1 (8.3%) |
Histones | 6 (12.5%) | 0 | |
Cell Membrane | 0 | 0 | |
Enzymes | 5 (10.4%) | 0 | |
Transcription/translation | 2 (4.2%) | 0 | |
Other/Unknown | 7 (14.6%) | 1 (8.3%) | |
Total | 39 (81.2%) | 2 (16.6%) |
Numbers in brackets indicate percentage of total protein number. A full list of differentially abundant proteins is available in Supplementary Table 3.