Table 1. The top ten Ingenuity Pathway Analysis (IPA) ‘Canonical Pathways’ enriched with differentially expressed genes in the colon of rats mono-associated with AGR1487 compared to rats mono-associated with AGR1485.

IPA Canonical Pathways	P-value	Ratio
RAR Activation	0.002	0.023
Retinoate Biosynthesis I	0.004	0.061
Ethanol Degradation II	0.004	0.061
Noradrenaline and Adrenaline Degradation	0.005	0.057
S-adenosyl-L-methionine Biosynthesis	0.009	0.333
EGF Signalling	0.011	0.036
Arginine Degradation I (Arginase Pathway)	0.013	0.250
Serotonin Degradation	0.013	0.033
NF-κB Signalling	0.014	0.017
Agrin Interactions at Neuromuscular Junction	0.017	0.029

The ratio indicates the number of differentially expressed genes that map to the pathway divided by the total number of genes that map to the canonical pathway.