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. 2016 Feb 2;7:10593. doi: 10.1038/ncomms10593

Figure 8. iNSC-sTR treatment of patient-derived GBMs.

Figure 8

(a) Summary data of the patient-derived cancer cells lines 7030, 7081, 7063, GBM6 treated with increasing volumes of conditioned media from iNSC-sTR or control iNSC-GFP cells. Cell viability was assessed 24 h after treatment. (b) Representative bioluminescent images and summary data showing the progression of 7063 xenografts treated with iNSC-sTR or iNSC-GFP (n=12 per group). (c) Representative fluorescent micrographs of the brain sections from control- or iNSC-sTR-treated mice bearing 7063 GBM xenografts (magenta). (d) Ki-67 (green) staining of post-mortem tissue sections 7063 (magenta) tumours treated with iNSC-control or iNSC-sTR. Colocalization of the signal is shown in white. Scale bar in c, 1,000 and 100 μm in d. Data in a are from three independent experiments. Data in b are n=12 per group. In a,b, *P<0.05 by repeated measures two-way ANOVA.