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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Environ Res. 2015 Oct 19;143(0 0):123–130. doi: 10.1016/j.envres.2015.10.001

Table 4.

Estimated regression coefficient (95% CI) of blood %As metabolites as predictors of respective urinary %As metabolites in linear models, stratified by renal function.

Normal eGFR
(≥90 ml/min/1.73 m2)		 Reduced eGFR
(<90 ml/min/1.73 m2)		 pa
Total sampleb N=166 N=126
%InAsc 1.29 (0.97, 1.62) 0.90 (0.64, 1.15) 0.06
%MMA 0.32 (0.19, 0.45) 0.33 (0.17, 0.48) 0.96
%DMA 0.88 (0.69, 1.07) 0.82 (0.64, 0.99) 0.62
Mend N=58 N=88
%InAsc 1.10 (0.62, 1.57) 0.89 (0.58, 1.20) 0.47
%MMA 0.24 (−0.04, 0.52) 0.39 (0.18, 0.60) 0.40
%DMA 1.14 (0.82, 1.45) 0.92 (0.69, 1.15) 0.27
Womend N=108 N=38
%InAsc 1.37 (0.93, 1.81) 0.83 (0.28, 1.37) 0.12
%MMA 0.34 (0.19, 0.50) 0.21 (−0.01, 0.44) 0.33
%DMA 0.80 (0.56, 1.04) 0.61 (0.30, 0.93) 0.34
a

p-value from Wald test for difference in regression coefficient of interest between participants with normal and reduced renal function.

b

Models adjusted for ln(water As) and sex.

c

Blood and urinary %InAs are natural log transformed.

d

Models adjusted for ln(water As).