Table 2.

The non-synonymous single amino acid variation in MYH1 from Jeju Native Pig and Berkshire

Chr. position	CDS	Position and substitutions of amino acid	SIFT	PROVEAN (cutoff = −2.5)	PolyPhen2	I-Mutant 3.0 (DDGaKcal/mole)	PANTHERb
							subPSEC	Pdeleterious
JNP
12.57978043	17	M881R	0.00	−3.116	0.544	−0.62	−2.39	0.35
12.57978052	17	L884T	0.00	−3.652	0.964	−1.92	−4.25	0.77
12.57978091	17	A897T	0.03	−2.363	0.001	−0.66	−2.03	0.27
12.57979374	18	K970A	0.00	−5.027	0.913	−0.25	−2.04	0.27
12.57979379	18	K972C	0.00	−6.630	1.000	−0.31	−5.38	0.91
12.57979382	18	H973G	0.00	−7.257	0.443	−0.44	−2.55	0.38
12.57979388	18	T975V	0.00	−3.986	0.023	−0.29	−2.64	0.41
12.57979406	18	N981G	0.00	−4.794	0.053	−0.61	−3.08	0.52
12.57981606	23	Q1285C	0.00	−4.127	0.889	−0.82	−3.88	0.70
12.57981608	23	T1286P	0.01	−3.669	0.976	−0.36	−2.92	0.48
Berkshire
12.57978091	17	A897T	0.03	−2.207	0.724	−0.66	−2.03	0.27
12.57979342	18	H973G	0.00	−7.257	1.000	−0.44	−2.55	0.38
12.57981608	23	T1286P	0.01	−3.669	0.976	−0.36	−2.92	0.48

^aDDG < −0.5: Large Decrease of Stability; DDG > 0.5: Large Increase of Stability

^bA cutoff of −3 corresponds to a 50 % probability that a score is deleterious