. 2016 Jan 20;11(2):254–261. doi: 10.2215/CJN.05760515

Table 4.

Spearman correlations (P values) between clinical and morphometric variables in 111 Pima Indians with type 2 diabetes mellitus

Characteristic	GS, %	V_G, μm³	VvInt, %	VvMes, %	S_V, μ²/μ³	TFS, μ²	GBM, nm	E + M, No.	Podo, No.	FPW, nm	PD, %	Fen, %
Age, yr	0.40 (<0.001)^a	−0.27 (0.004)^a	0.24 (0.01)^a	−0.01 (0.91)	0.02 (0.85)	−0.14 (0.14)	−0.19 (0.04)^a	−0.20 (0.03)^a	−0.21 (0.03)^a	0.11 (0.26)	0.04 (0.70)	0.14 (0.15)
Diabetes duration, yr	0.31 (0.001)^a	−0.11 (0.27)	0.40 (<0.001)^a	0.42 (<0.001)^a	−0.31 (0.001)^a	−0.37 (<0.001)^a	0.24 (0.01)^a	0.12 (0.19)	−0.21 (0.03)^a	0.166 (0.08)	0.13 (0.17)	−0.22 (0.02)^a
MAP, mmHg	−0.01 (0.95)	0.21 (0.03)^a	0.11 (0.26)	0.22 (0.02)^a	−0.13 (0.17)	−0.03 (0.78)	0.24 (0.01)^a	0.35 (<0.001)^a	0.05 (0.57)	0.25 (0.01)^a	0.09 (0.34)	−0.17 (0.07)
BMI, kg/m²	0.05 (0.63)	0.08 (0.39)	−0.18 (0.06)	−0.23 (0.01)^a	0.19 (0.05)	0.23 (0.02)^a	−0.28 (0.003)^a	−0.02 (0.81)	0.01 (0.92)	−0.15 (0.12)	−0.05 (0.59)	−0.01 (0.92)
HbA1c, %	−0.31 (0.001)^a	0.26 (0.01)^a	0.08 (0.42)	0.27 (0.004)^a	−0.16 (0.10)	−0.02 (0.87)	0.34 (<0.001)^a	0.29 (0.002)	0.06 (0.53)	0.17 (0.07)	0.07 (0.44)	−0.19 (0.05)
ACR, mg/g	0.07 (0.44)	0.34 (<0.001)^a	0.23 (0.01)^a	0.54 (<0.001)^a	−0.49 (<0.001)^a	−0.23 (0.02)^a	0.54 (<0.001)^a	0.43 (<0.001)^a	−0.15 (0.11)	0.28 (0.003)^a	0.12 (0.20)	−0.43 (<0.001)^a
GFR, ml/min	−0.29 (0.002)^a	0.34 (<0.001)^a	−0.29 (0.002)^a	−0.31 (<0.001)^a	0.27 (0.004)^a	0.46 (<0.001)^a	−0.10 (0.32)	0.11 (0.27)	0.26 (0.01)^a	−0.11 (0.25)	−0.07 (0.46)	0.22 (0.02)^a

GS, global sclerosis; V_G, mean glomerular volume; VvInt, cortical interstitial fractional volume; VvMes, mesangial fractional volume; S_V, glomerular filtration surface density; TFS, total filtration surface; GBM, glomerular basement membrane width; E + M, endothelial and mesangial cells per glomerulus; Podo, podocytes per glomerulus; FPW, foot process width; PD, podocyte detachment along glomerular basement membrane; Fen, fenestrated endothelial cells; MAP, mean arterial pressure; BMI, body mass index; HbA1c, hemoglobin A1c; ACR, albumin-to-creatinine ratio.

P values <0.05.