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(A) The CpG island within the miR-34c promoter region was hyper-methylated in CRC cells. DAC treatment induced partial demethylation indicated by the appearance of unmethylation bands (M: methylation, U: unmethylation). (B) DAC treatment elicited remarkable increase in miR-34c expression, which was much more tremendous in HT-29 cells (**P<0.01 compared with control).
