Fig. 3.
Mass spectrometric analyses of Cer[EOS]. (A) Cer[EOS] with fatty acid residues ranging from h30:0-18:2 to h36:0-18:2 on epidermal surface. The relative amount of Cer[EOS] (in mol% of all ceramides) is strongly diminished on the epidermal surface of Cx26S17F mice. n = 3. (B) Cer[EOS] composition (mol% of all ceramides) in lipid extracts from whole epidermis. Relative amounts of Cer[EOS] are only slightly decreased when extracted from all epidermal layers. n = 4. Cer: ceramide; E: esterified with linoleic acid; O: ω-hydroxylated fatty acid; S: sphingosine long chain base.