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. 2016 Feb 4;11(2):e0148580. doi: 10.1371/journal.pone.0148580

Fig 2. Correlation of miRNA-21 to patient follow-up.

Fig 2

Disease-free survival with regard to liver metastasis (LiMe) and overall survival illustrated with the Kaplan-Meier method. (a) Comparison of overall survival between a miRNA-21 high and low expression group in colorectal carcinomas (PrTu). There is a trend towards shorter survival with higher miRNA-21 levels, although not significant (p = 0.27). (b) The patients with metachronous LiMe are sub-divided into a high and low miRNA-21 expression group in PrTu. By trend, high miRNA-21 led to earlier manifestation of LiMe (p = 0.20). (c) A comparison of survival between a high and a low miRNA-21 group in LiMe shows no significant difference (p = 0.44). (d) Survival does not differ significantly between those patients with higher miRNA-21 in the primary tumor and those with higher miRNA-21 in LiMe.