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. 2015 Sep 25;6(33):34206–34220. doi: 10.18632/oncotarget.5275

Figure 3. a2V and Notch1 are activated in human breast tumors.

Figure 3

Tissue microarray containing human breast tumors and normal breast tissues (control) were used to immunolocalize A. a2V and B. Notch1. Tumors were grouped by receptor-defined subtype. 12 sections per subtype were analyzed. Brown staining - DAB, counterstain - hematoxylin. Original magnification: 400X. Corresponding scatter dot plots show immunostaining index score ((ISIS) = Stained area score (SAS) × Immunostaining intensity score (IIS)) for C. a2V and D. Notch1. Data represent mean ± standard error, n = 12. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001 between a pair of subtypes. DAB: 3,3′ Diaminobenzidine.