Table 3. Univariate analysis of overall survival in patients treated with RT and temozolomide.
Variable | Hazard Ratio (95% CI) | p-value |
---|---|---|
RSI RR vs. RS | 1.34 (0.91,1.98) | 0.14 |
MGMT Expression High vs. Low | 1.7 (1.23,2.35) | 0.002 |
Age 50+ vs. 50 | 1.76 (1.2,2.59) | 0.004 |
ECOG 24 vs. 01 | 1.73 (1.14,2.64) | 0.01 |
ECOG Unknown vs. 01 | 1.23 (0.73,2.07) | 0.43 |
Gender Male vs. Female | 1.07 (0.76,1.51) | 0.71 |
Race Black vs. Asian/White | 1.01 (0.45,2.29) | 0.98 |
Race Unknown vs. Asian White | 1.53 (0.48,4.82) | 0.47 |
CI = Confidence Interval
RT = Radiotherapy
RSI = Radiosensitivity index
RS = Radiosensitive
RR = Radioresistant
MGMT = O(6)-Methylguanine-DNA methyltransferase
ECOG = Eastern Cooperative Oncology Group Performance Status