Table 4. Multivariate analysis of overall survival in patients treated with RT and temozolomide.
| Variable | Hazard Ratio (95% CI) | p-value |
|---|---|---|
| RSI: RR vs. RS | 1.64 (1.08,2.5) | 0.02 |
| MGMT Expression: High vs. Low | 1.99 (1.39,2.9) | 0.0002 |
| Age: 50+ vs. 50 | 1.54 (1,2.31) | 0.03 |
| ECOG: 24 vs. 01 | 1.74 (1.12,2.69) | 0.01 |
| ECOG: Unknown vs. 01 | 1.05 (0.6,1.81) | 0.87 |
CI = Confidence Interval
RSI = Radiosensitivity Index
RS = Radiosensitive
RR = Radioresistant
MGMT = O(6)-Methylguanine-DNA methyltransferase
ECOG = Eastern Cooperative Oncology Group Performance Status