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. 2015 Sep 27;6(33):34774–34787. doi: 10.18632/oncotarget.5793

Table 2. Incidence of lung metastases in athymic nude mice treated with R-LM249-infected FM-MSCs.

Treatmenta Lung metastases
Incidence (%) Median Range
Untreated 13/19 (68%) 5 0 – 157
FM-MSCs 13/18 (72%) 9.5 0 - >200
R-LM249 FM-MSCs 3/19* (16%) 0* 0 - 31
a

Mice received an i.v. injection of SK-OV-3 cells; one week later they received an i.v. injection of R-LM249-infected FM-MSCs (R-LM249 FM-MSCs), uninfected FM-MSCs (FM-MSCs), or vehicle (Untreated). Mice were sacrificed 9 weeks later.

*

Significance of difference versus Untreated and FM-MSCs is p<0.01 (Fisher's Exact test for frequency and Mann–Whitney rank sum test for metastasis number).