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. 2015 Sep 28;6(33):34788–34799. doi: 10.18632/oncotarget.5858

Figure 7. Proposed intracellular transduction mechanisms underlying PAR1-induced inhibition of Hippo-YAP pathway and EMT through Snail.

Figure 7

Activation of the PAR1 by the selective PAR1-AP TFLLR-NH2 results in Rho activation mediating the inhibition of Hippo-YAP cascades leading to EMT via Snail.