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Downregulation of expression of p-AKT (ser473) and Bcl-2 were detected in CK2α-knockdown Bel-7402 and HepG2 cells. The expression of P53, p-P53 (ser15), caspase3, cleaved caspase3, cleaved caspase9, cleaved PARP, Bax were increased in CK2α-knockdown Bel-7402 and HepG2 cells.
