Table 1. Correlation between CK2α expression and clinicopathological variables of 98 patients with HCC.
Clinicopathologic variable | CK2α expression | χ2 | P | ||
---|---|---|---|---|---|
N | Low | High | |||
All cases | 98 | 56 | 42 | ||
Age (years) | 3.16 | 0.075 | |||
<50 | 51 | 34 | 17 | ||
≥50 | 47 | 23 | 24 | ||
Sex | 0.015 | 0.901 | |||
Male | 88 | 51 | 37 | ||
Female | 10 | 6 | 4 | ||
Tumor size(cm) | 1.478 | 0.224 | |||
<5 | 33 | 22 | 11 | ||
≥5 | 65 | 35 | 30 | ||
Histological grade | 9.453 | 0.009a | |||
Good | 37 | 28 | 9 | ||
Moderate | 28 | 16 | 12 | ||
Poor | 33 | 13 | 20 | ||
Liver cirrhosis | 1.781 | 0.182 | |||
No | 26 | 18 | 8 | ||
Yes | 72 | 39 | 33 | ||
HBV | 0.115 | 0.735 | |||
Negative | 13 | 7 | 6 | ||
Positive | 85 | 50 | 35 | ||
AFP (ng/mL) | 1.349 | 0.245 | |||
Negative (≤400) | 53 | 28 | 25 | ||
Positive (>400) | 45 | 29 | 16 | ||
Tumor capsule | 1.087 | 0.297 | |||
Intact | 32 | 21 | 11 | ||
Absent and not intact | 66 | 36 | 30 | ||
Vascular | 0.004 | 0.952 | |||
No | 81 | 47 | 34 | ||
Yes | 17 | 10 | 7 | ||
TNM stage) | 7.365 | 0.007a | |||
Stage I | 54 | 38 | 16 | ||
Stage II and III | 44 | 19 | 25 | ||
Distant metastasis | 4.436 | 0.035a | |||
No | 77 | 49 | 28 | ||
Yes | 21 | 8 | 13 |
AFP, alfa fetoprotein; HBV, hepatitis B virus.
P < 0.05.