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. 2015 Sep 30;6(33):34941–34952. doi: 10.18632/oncotarget.5472

Figure 5. Effects of miR-23a on caspase-3/7 activity and apoptosis in SNU-387 cells.

Figure 5

A. Caspase 3/7 activity were analyzed in SNU-387 cells transfected with miR-23a mimic or anti-miR-23a, or with E2 treatment +/− ERα knockdown (**p < 0.005 and *p < 0.05) for 24 hours. Similarly, effect of miR-23a mimic, anti-miR-23a, and E2 treatment on B. caspase-7 mRNA and protein expression; C. caspase-3 mRNA expression; and D. pro-caspase-3 (32KD) and active caspase-3 (17KD) protein levels were analyzed 24 hours after transfection or treatment in SNU-387 cells. Data are mean values ± SEM from three independent experiments (***p < 0.0001, **p < 0.001 and *p < 0.01).