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. 2015 Oct 8;6(33):35051–35062. doi: 10.18632/oncotarget.6036

Table 4. Acute and late toxicity.

Acute toxicity (Total) G0 G1-G2 G3 G4 Not Available
Radiation dermatitis 0 44 4 1 7
By Subgroup Gross disease 0 23 5 0 4
No gross disease 0 13 3 0 0
Mastectomy 0 25 4 0 4
BCS 0 15 2 0 0
Hypofractionation 0 10 4 0 4
Standard fractionation 0 22 2 0 0
Late toxicity (Total)
Fibrosis 19 11 4 0 15
Telangiectasia 27 4 3 0 15
Necrosis 33 0 0 1 15
Lymphedema 30 4 0 0 15
Hyper/Hypopigmentation 28 6 0 0 15
Neumonitis 32 2 0 0 15
By Subgroup Gross disease 4 14 2 2 10
No gross disease 5 6 1 2 2
Mastectomy 4 10 2 2 15
BCS 4 9 1 1 2
Hypofractionation 2 3 1 2 10
Standard fractionation 5 16 2 1 0

Acute toxicity reported for 56 re-irradiations using CTCAE 3.0. Late toxicity reported for 47 patients (2 with bilateral disease) that had at least one course of re-irradiation.