Figure 2. EGCG-dependent inhibition of α-amylase and α-glucosidase activity in vitro (a, b) and in vivo (c, d) and decrease of glucose levels in vivo (e).

Dose-dependent inhibition of a. α-amylase and b. α-glucosidase by EGCG in vitro. The data are expressed as the mean + SEM (n = 3). c. α-amylase activity, d. α-glucosidase activity, and e. glucose levels of male W¹¹¹⁸ Drosophila melanogaster relative to fly weights. Flies were reared on an EGCG (10 mg/ml)-supplemented or control diet for 10 days. The data are expressed as the mean + SEM (n = 5–6, indicating extraction from 5–6 × 5 flies). * indicates significant differences in EGCG-treated flies compared to flies fed control medium for 10 days (p < 0.05, Student's t-test).