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. 2015 Sep 1;6(31):30818–30830. doi: 10.18632/oncotarget.5067

Figure 6. CXCR7 expression in BrC tissues and its correlation with miR-101 expression.

Figure 6

A. A qRT-PCR analysis of CXCR7 levels in BrC tissues (BCT, n = 72) and corresponding non-cancerous tissues (NCT, n = 72). B. A qRT-PCR analysis of CXCR7 mRNA levels in BrC tissues with (n = 51) or without (n = 37) lymphatic metastasis. C. A qRT-PCR analysis of CXCR7 mRNA levels in BrC patients at different clinical stages (WHO I, n = 11; WHO II, n = 30; and WHO III, n = 46). D. Representative IHC images of CXCR7 in NCT and BCT with various scores (100× and 200× magnifications). E. A qRT-PCR analysis of CXCR7 mRNA levels in BrC patients with low and high miR-101 levels. F. IHC scores of the CXCR7 protein level in patients with low and high miR-101 levels. Scoring was based on the percentage of positive cells with the following staining intensities: less than 5% scored 0, 5–20% scored 1, 20–50% scored 2, 50–75% scored 3, and > 75% scored 4. (A–D, F) Data are represented as the mean ± SD of three replicates. *P < 0.05 and **P < 0.01.