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. 2015 Sep 4;6(31):30968–30974. doi: 10.18632/oncotarget.5038

Table 1. Gene alterations in primary and recurrent GBM according to their molecular subtypes.

Primary glioblastoma Recurrent glioblastoma
Proneural Neural Classical Mesenchymal Proneural Neural Classical Mesenchymal
No. of patients 13 7 32 36 5 2 5 10
IDH 1 mutation 10 0 2 0 4 0 1 1
TP53 mutation 5 5 14 20 1 1 4 7
EGFR mutation 4 1 8 10 2 0 1 1
ATRX mutation 2 2 2 3 0 0 1 3