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. 2015 Aug 17;6(31):30993–31006. doi: 10.18632/oncotarget.5206

Figure 3. Transcriptional regulation of human CDX2 by Ascl2.

Figure 3

A. A schematic representation of the human CDX2 promoter constructs used in this study. Seven promoter deletion-luciferase constructs were generated to identify the sites of transcriptional regulation within the human CDX2 promoter that respond to Ascl2 knockdown. B. shRNA-Ascl2/HT-29 and shRNA-Ctr/HT-29 cells were transfected with CDX2 constructs to identify the sites of transcriptional regulation within the human CDX2 promoter. C. shRNA-Ascl2/LS174T and shRNA-Ctr/LS174T cells were transfected with CDX2 constructs to identify the sites of transcriptional regulation within the human CDX2 promoter. Data are presented as the mean±S.E. of three independent experiments (*: p < 0.05; **: p < 0.01).