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. 2015 Sep 22;6(31):31104–31118. doi: 10.18632/oncotarget.5093

Table 2. Patient blood levels of autophagic drugs.

MW Peak Molarity Trough Molarity Reference (PMID)
Metformin 165.62 1600 ng/mL 9.66E-06 273 ng/mL 1.65E-06 22864111
Chloroquine 515.86 4500 ng/mL 8.76E-06 600 ng/mL 1.16E-06 3289601
Nelfinavir 663.89 3820 ng/mL 9.94E-06 125 ng/mL 3.27E-07 NDA 21-503
Rapamycin 914.2 30 ng/mL 1.15E-07 23 ng/mL 8.80E-08 9721433
Dasatinib 488.1 129 ng/mL 2.64E-07 8.7 ng/mL 1.78E-08 22837181