Table 2. Patient blood levels of autophagic drugs.
MW | Peak | Molarity | Trough | Molarity | Reference (PMID) | |||
---|---|---|---|---|---|---|---|---|
Metformin | 165.62 | 1600 | ng/mL | 9.66E-06 | 273 | ng/mL | 1.65E-06 | 22864111 |
Chloroquine | 515.86 | 4500 | ng/mL | 8.76E-06 | 600 | ng/mL | 1.16E-06 | 3289601 |
Nelfinavir | 663.89 | 3820 | ng/mL | 9.94E-06 | 125 | ng/mL | 3.27E-07 | NDA 21-503 |
Rapamycin | 914.2 | 30 | ng/mL | 1.15E-07 | 23 | ng/mL | 8.80E-08 | 9721433 |
Dasatinib | 488.1 | 129 | ng/mL | 2.64E-07 | 8.7 | ng/mL | 1.78E-08 | 22837181 |