Skip to main content
. 2015 Sep 5;6(31):31216–31232. doi: 10.18632/oncotarget.5157

Figure 7. Effect of apigenin on sub-cellular distribution of IKKα, IKKβ and its phosphorylated forms in human prostate cancer cells.

Figure 7

A. PC-3 and B. 22Rv1 cells were treated with indicated doses of apigenin for 16 h; subjected to preparation of cytosolic and nuclear fractions and protein expression of IKKα, IKKβ and their phosphorylation was determined by Western blot analysis. A significant decrease in p-IKKα in the nuclear fraction and simultaneous increase in p-IKKα expression in the cytosol after apigenin treatment, compared to untreated group in both cell lines. Details are described in ‘materials and methods’ section.