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. 2015 Sep 3;6(31):31233–31240. doi: 10.18632/oncotarget.5180

Figure 1. A low protein diet or intermittent fasting regimen slows tumor growth rate in a mouse model of breast cancer.

Figure 1

A. Weights of 6 week old female mice placed on diets containing either 21% or 7% protein, which were fed either ad libitum (AL) or with intermittent, alternate day fasting (IF). Arrow indicates time of tumor implantation on day 29. B. Tumor volumes were measured weekly starting 20 days after tumor cell implantation. (n = 7–10 mice per group, a = p ≤ 0.05, b = p ≤ 0.09, 21% AL vs. all other groups; c = p < 0.008, 7% AL vs. 21% IF; d = p < 0.006, 7% AL vs 7% IF). Data in A-B for AL fed mice was previously published in part [7] and is shown here for comparison. C. Growth rates of tumors in mice on each indicated diet was calculated using the method of Laird and Ware [34] from tumor volumes measured 3–12 weeks after tumor implantation (n = 9–10 mice per group, p < 0.0001).