Skip to main content
. 2015 Sep 4;6(31):31241–31254. doi: 10.18632/oncotarget.5160

Figure 2. SOX9 upregulation correlates with poor prognosis of human ESCC.

Figure 2

A. Representative images of IHC analyses of ESCC specimens (clinical Stage I–IV tumors) compared with normal esophageal tissue (left, × 200 magnification; right, × 400 magnification). IHC analyses were performed in two independent experiments on sections from each specimen, with similar results. B. Statistical analyses of the mean optical density (MOD) of SOX9 staining between normal esophageal tissue and ESCC specimens from different clinical stages. Bars represent the mean ± SD of three independent experiments. *P < 0.05. C. Kaplan–Meier curves from univariate analyses (log-rank) of patients with low vs. high SOX9 expression. P-values were calculated using the log-rank test.